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Koellensperger G, Groeger M, Zinkl D, Petzelbauer P, Hann S J. Anal. At. Spectrom., 2009, 24, 97102 [pdf-file in new window (380 KB) >>] or [Original Article in 'JAAS' (subscription required) >>] Gröger M, Pasteiner W, Ignatyev G, Matt U, Knapp S, Atrasheuskaya A, Bukin E, Friedl P, Zinkl D, Hofer-Warbinek R, Zacharowski K, Petzelbauer P, Reingruber S PLoS ONE 4(4): e5391. doi:10.1371/journal.pone.0005391 [pdf-file in new window (3,2 MB) >>] or [go to PLoS ONE >>] Effect of intravenous FX06 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction
Results of the F.I.R.E. (Efficacy of FX06 in the prevention of myocardial reperfusion injury) trial Atar D, Petzelbauer P, Schwitter J, Huber K, Rensing B, Kasprzak JD, Butter C, Grip L, Hansen PR, Süselbeck T, Clemmensen PM, Marin-Galiano M, Geudelin B, Buser BT, for the F.I.R.E. Investigators Journal of the American College of Cardiology (2009) 53:720-729 Bß15-42 (FX06) reduces pulmonary, myocardial, liver, and small intestine damage in a pig model of hemorrhagic shock and reperfusion
Roesner JP, Petzelbauer P, Koch A, Tran N, Iber T, Vagts DA, Scheeren TWL, Vollmar B, Nöldge-Schomburg GEF, Zacharowski, K Crit Care Med 2009 Vol. 37, No. 2 A double blind, single centre, sub-chronic reperfusion trial evaluating FX06 following haemorrhagic shock in pigs
Roesner JP, Petzelbauer P, Koch A, Tran N, Iber T, Mutz C, Vollmar B, Nöldge-Schomburg GEF, Zacharowski K Resuscitation 2009; 80:264271 ![]() The fibrin-derived peptide Bbeta15-42 is cardioprotective in a pig model of myocardial ischemia-reperfusion injury Roesner JP, Petzelbauer P, Koch A, Mersmann J, Zacharowski PA, Boehm O, Reingruber S, Pasteiner W, Mascher HD, Wolzt M, Barthuber C, Noldge-Schomburg GE, Scheeren TW, Zacharowski K Crit Care Med. 2007 May 22, Epub Ahead of Print [PubMed Abstract >>] [Original Article in 'Critical Care Medicine' (subscription required) >>] ![]() The effects of the fibrin-derived peptide Bbeta15-42 in acute and chronic rodent models of myocardial ischemia-reperfusion Zacharowski K, Zacharowski PA, Friedl P, Mastan P, Koch A, Boehm O, Rother RP, Reingruber S, Henning R, Emeis JJ, Petzelbauer P Shock. 2007 Jun;27(6):631-63 [PubMed Abstract >>] [Original Article in 'Shock' (subscription required) >>] ![]() Neue Überlegungen zu Entzündung und Gerinnung [New reflections on inflammation and coagulation] Zacharowski, K Der Anaesthesist. 2007 Mar 16 (DOI: 10.1007/s00101-007-1163-3) [PubMed Abstract >>] [Original Article in 'Der Anaesthesist' (subscription required) >>] ![]() FX06 (fibrin-derived peptide Bbeta15-42) - A potential candidate for myocardial reperfusion therapy Henning R, Zacharowski K, Petzelbauer P Drugs Fut. 2006, 31(9):811-818 (DOI: 10.1358/dof.2006.031.09.1025670) [Abstract >>] [Original Article in 'Drugs of the Future' (subscription required) >>] ![]() Rationale and Design of the 'F.I.R.E.' Study. A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Measure the Effect of FX06 (a Fibrin-Derived Peptide Bbeta(15-42)) on Ischemia-Reperfusion Injury in Patients with Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Atar D, Huber K, Rupprecht HJ, Kopecky SL, Schwitter J, Theek C, Brandl K, Henning R, Geudelin B. Cardiology 2006 Oct 2;108(2):117-123 (DOI: 10.1159/000095982) [PubMed Abstract >>] [Original Article in 'Cardiology' (subscription required) >>] ![]() Fibrin(ogen) and its fragments in the pathophysiology and treatment of myocardial infarction Zacharowski K, Zacharowski P, Reingruber S, Petzelbauer P J. Mol. Med. 2006 June;84(6):469-477 [PubMed Abstract >>] [Original Article in 'J. Mol. Med.' (subscription required) >>] ![]() The fibrin-derived peptide Bbeta15-42 protects the myocardium against ischemia-reperfusion injury. Petzelbauer P, Zacharowski PA, Miyazaki Y, Friedl P, Wickenhauser G, Castellino FJ, Groger M, Wolff K, Zacharowski K. Nat. Med. 2005 Mar;11(3):298-304 [PubMed Abstract >>] [Original Article in 'Nature Medicine' (subscription required) >>]
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