Quantification of elemental labeled peptides in cellular uptake studies
Koellensperger G, Groeger M, Zinkl D, Petzelbauer P, Hann S
J. Anal. At. Spectrom., 2009, 24, 97102
www.fibrexmedical.com/pdf/JAAS_FX_2009.pdf
Original Article in 'JAAS' (subscription required):
www.rsc.org/publishing/journals/JA/article.asp?doi=b807397j
Peptide Bß15-42 Preserves Endothelial Barrier Function in Shock
Gröger M, Pasteiner W, Ignatyev G, Matt U, Knapp S, Atrasheuskaya A, Bukin E, Friedl P, Zinkl D, Hofer-Warbinek R, Zacharowski K, Petzelbauer P, Reingruber S
PLoS ONE 4(4): e5391. doi:10.1371/journal.pone.0005391
www.fibrexmedical.com/pdf/PLoS_ONE_4_2009.pdf
or
http://dx.plos.org/10.1371/journal.pone.0005391
Effect of intravenous FX06 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction
Results of the F.I.R.E. (Efficacy of FX06 in the prevention of myocardial reperfusion injury) trial
Atar D, Petzelbauer P, Schwitter J, Huber K, Rensing B, Kasprzak JD, Butter C, Grip L, Hansen PR, Süselbeck T, Clemmensen PM, Marin-Galiano M, Geudelin B, Buser BT, for the F.I.R.E. Investigators
Journal of the American College of Cardiology (2009) 53:720-729
www.fibrexmedical.com/pdf/JACC_2009.pdf
Bß15-42 (FX06) reduces pulmonary, myocardial, liver, and small intestine damage in a pig model of hemorrhagic shock and reperfusion
Roesner JP, Petzelbauer P, Koch A, Tran N, Iber T, Vagts DA, Scheeren TWL, Vollmar B, Nöldge-Schomburg GEF, Zacharowski, K
Crit Care Med 2009 Vol. 37, No. 2
www.fibrexmedical.com/pdf/CCM_2009.pdf
A double blind, single centre, sub-chronic reperfusion trial evaluating FX06 following haemorrhagic shock in pigs
Roesner JP, Petzelbauer P, Koch A, Tran N, Iber T, Mutz C, Vollmar B, Nöldge-Schomburg GEF, Zacharowski K
Resuscitation 2009; 80:264271
www.fibrexmedical.com/pdf/Resuscitation_2009.pdf
The fibrin-derived peptide Bbeta15-42 is cardioprotective in a pig model of myocardial ischemia-reperfusion injury
Roesner JP, Petzelbauer P, Koch A, Mersmann J, Zacharowski PA, Boehm O, Reingruber S, Pasteiner W, Mascher HD, Wolzt M, Barthuber C, Noldge-Schomburg GE, Scheeren TW, Zacharowski K
Crit Care Med. 2007 May 22, Epub Ahead of Print
PubMed Abstract:
www.ncbi.nlm.nih.gov/entrez/
query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17522584
Original Article in 'Crit Care Med' (subscription required):
www.ccmjournal.com/pt/re/ccm/abstract.00003246-900000000-99646.htm
The effects of the fibrin-derived peptide Bbeta15-42 in acute and chronic rodent models of myocardial ischemia-reperfusion
Zacharowski K, Zacharowski PA, Friedl P, Mastan P, Koch A, Boehm O, Rother RP, Reingruber S, Henning R, Emeis JJ, Petzelbauer P
Shock. 2007 Jun;27(6):631-63
PubMed Abstract:
www.ncbi.nlm.nih.gov/entrez/
query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17505302
Original Article in 'Shock' (subscription required): www.shockjournal.com/pt/re/shock/abstract.00024382-200706000-00007.htm
Neue Überlegungen zu Entzündung und Gerinnung
[New reflections on inflammation and coagulation]
Zacharowski, K
Der Anaesthesist. 2007 Mar 16 (DOI: 10.1007/s00101-007-1163-3)
PubMed Abstract:
www.ncbi.nlm.nih.gov/entrez/
query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17364187
Original Article in 'Der Anaesthesist' (subscription required):
www.springerlink.com/content/p744477r3326k618/?typ=fulltext&file=CRD2007108002117
FX06 (fibrin-derived peptide Bbeta15-42) - A potential candidate for myocardial reperfusion therapy
Henning R, Zacharowski K, Petzelbauer P
Drugs Fut. 2006, 31(9): 811-818 (DOI: 10.1358/dof.2006.031.09.1025670)
Abstract and link to original article in 'Drugs of the Future': http://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_summary_pr?
p_JournalId=2&p_RefId=1025670&p_IsPs=N
Rationale and Design of the 'F.I.R.E.' Study.
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Measure the Effect of FX06 (a Fibrin-Derived Peptide Bbeta(15-42)) on Ischemia-Reperfusion Injury in Patients with Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.
Atar D, Huber K, Rupprecht HJ, Kopecky SL, Schwitter J, Theek C, Brandl K, Henning R, Geudelin B.
Cardiology 2006 Oct 2;108(2):117-123 (DOI: 10.1159/000095982)
PubMed Abstract:
www.ncbi.nlm.nih.gov/entrez/
query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17019083
Original Article in Cardiology (subscription required):
http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=CRD2007108002117
Fibrin(ogen) and its fragments in the pathophysiology and treatment of myocardial infarction
Zacharowski K, Zacharowski P, Reingruber S, Petzelbauer P
J. Mol. Med. 2006 June;84(6):469-477
PubMed Abstract:
www.ncbi.nlm.nih.gov/entrez/
query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16733765
Original Article in J. Mol. Med. (subscription required):
http://dx.doi.org/10.1007/s00109-006-0051-7
The fibrin-derived peptide Bbeta15-42 protects the myocardium against ischemia-reperfusion injury.
Petzelbauer P, Zacharowski PA, Miyazaki Y, Friedl P, Wickenhauser G, Castellino FJ, Groger M, Wolff K, Zacharowski K.
Nat. Med. 2005 Mar;11(3):298-304
PubMed Abstract:
www.ncbi.nlm.nih.gov/entrez/
query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15723073
Original Article in Nature Medicine (subscription required):
www.nature.com/nm/journal/v11/n3/index.html
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